| 发明名称 |
Piperidinyl targeting compounds that selectively bind integrins |
| 摘要 |
The present invention relates to the synthesis and biological application of piperidinoyl carboxylic acid integrin antagonists affinity moiety of IFormula (I): and Formula (II): These affinity moieties maybe used with imaging agents or liposomes to target cells that express the alphavbeta3, alphavbeta5, or alphavbeta6 integrin receptors.
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| 申请公布号 |
US2004224986(A1) |
申请公布日期 |
2004.11.11 |
| 申请号 |
US20040782060 |
申请日期 |
2004.02.18 |
| 申请人 |
DE CORTE BART;KINNEY WILLIAM A.;MARYANOFF BRUCE E.;GHOSH SHYAMALI;LIU LI |
发明人 |
DE CORTE BART;KINNEY WILLIAM A.;MARYANOFF BRUCE E.;GHOSH SHYAMALI;LIU LI |
| 分类号 |
A61K31/4523;A61K45/06;A61P13/12;A61P17/06;A61P19/02;A61P19/10;A61P35/00;C07D401/12;C07D401/14;C07D405/14;C07D417/04;C07D471/04;(IPC1-7):A61K31/454;C0741/02 |
主分类号 |
A61K31/4523 |
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