NOVEL VACCINE COMPOSITIONS FOR PORCINE EPIDEMIC DIARRHEA VIRUS AND PORCINE DELTACORONAVIRUS
摘要
The present invention is directed to novel immunogenic compositions that protect swine from disease caused by porcine epidemic diarrhea virus (PEDV). The present invention is also directed to novel immunogenic compositions that protect swine from disease caused by porcine deltacoronavirus (PDCoV), alone or as combination vaccine to protect against PEDV. The compositions of the invention provide killed viruses whose effectiveness is enhanced by the selection of preferred adjuvants. Novel culture methods are also employed to increase reproducible yield of cultured viruses. Live vaccines are also provided from the Calaf14 PEDV isolate.
申请公布号
CA2954632(A1)
申请公布日期
2016.01.14
申请号
CA20152954632
申请日期
2015.07.08
申请人
ZOETIS SERVICES LLC
发明人
MARX, JACQUELINE GAYLE;HARDHAM, JOHN MORGAN;DOMINOWSKI, PAUL J.;RAPP GABRIELSON, VICKI JON;BALASCH SANUY, MONICA;CABANA SUMSI, MARTA;PLAJA DILME, LAIA;URNIZA HOSTENCH, ALICIA;ROMERO GALINDO, OSCAR