| 摘要 |
The present invention relates to a lung model device for inhalation toxicity testing, the provided lung model device for inhalation toxicity testing having a plurality of mesh tissue panels having lung cells attached thereto arranged inside a case so as to have a similar structure to a human lung, and the case having air and nanoparticles supplied therein through a separate respiratory operating unit, thereby enabling inhalation toxicity testing on nanoparticles to be simply and conveniently performed in an indirect way by determining changes in the state of the lung cells without using real laboratory animals, the device accordingly being capable of replacing regular nanoparticle inhalation toxicity testing devices, and the device having the plurality of mesh tissue panels arranged so that mesh tissue panels having a smaller lattice spacing size are sequentially positioned according to the nanoparticle inflow direction, thereby providing a structure similar to the structure of a real lung, and accordingly enabling the improvement of the accuracy of inhalation toxicity testing without using laboratory animals. |
