| 发明名称 |
Use of Faecalibacterium Prausnitzii Htf-f (DSM 26943) to Suppress Inflammation |
| 摘要 |
The present invention relates to medicine, particularly immunology and gastroenterology. Specifically, it relates to probiotic bacteria and extracts thereof for therapeutic use for the treatment of inflammatory disorders such as inflammatory bowel disease. Provided is a composition comprising as active ingredient Faecalibacterium prausnitzii strain HTF-F (DSM 26943) or an extract thereof comprising extracellular polymeric matrix (EPM), and an acceptable carrier, diluent or excipient. Also provided is an anti-inflammatory composition comprising EPM extracted from F. prausnitzii strain HTF-F, and a method for preparing the same. |
| 申请公布号 |
US2016000838(A1) |
申请公布日期 |
2016.01.07 |
| 申请号 |
US201414772519 |
申请日期 |
2014.03.05 |
| 申请人 |
RIJKSUNIVERSITEIT GRONINGEN ;ACADEMISCH ZIEKENHUIS GRONINGEN ;WAGENINGEN UNIVERSITEIT ;UNIVERSITY COURT OF THE UNIVERSITY OF ABERDEEN |
发明人 |
HARMSEN Hermanus Josef Martinus;KHAN Muhammad Tanweer;WELLS Jeremy;ROSSI Oriana;FLINT Harry James;DUNCAN Sylvia Helen |
| 分类号 |
A61K35/741;A23L1/03;A61K45/06 |
主分类号 |
A61K35/741 |
| 代理机构 |
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代理人 |
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| 主权项 |
1. A pharmaceutical, neutraceutical or food composition comprising as active ingredient Faecalibacterium prausnitzii strain HTF-F (deposited with the DSMZ on Mar. 1, 2013 under the accession number DSM 26943), and an acceptable carrier, diluent or excipient. |
| 地址 |
Groningen NL |
