| 发明名称 |
COMBINATION THERAPY INVOLVING ANTIBODIES AGAINST CLAUDIN 18.2 FOR TREATMENT OF CANCER |
| 摘要 |
The present invention provides a combination therapy for effectively treating and/or preventing diseases associated with cells expressing CLDN18.2, including cancer diseases such as pancreatic cancer and metastases thereof. |
| 申请公布号 |
US2015374789(A1) |
申请公布日期 |
2015.12.31 |
| 申请号 |
US201414769046 |
申请日期 |
2014.02.18 |
| 申请人 |
GANYMED PHARMACEUTICALS AG ;TRON-Translationale Onkologie an der Universitats- medizin der Johannes Gutenberg-Universitat Mainz. |
发明人 |
Sahin Ugur;Tureci Ozlem;Mitnacht-Kraus Rita;Woll Stefan;Jacobs Stefan;Heinz Cornelia |
| 分类号 |
A61K38/20;A61K45/06;C07K16/30;A61K31/7068;C07K16/28;A61K39/395;A61K31/555 |
主分类号 |
A61K38/20 |
| 代理机构 |
|
代理人 |
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| 主权项 |
1. A method of treating or preventing pancreatic cancer in a patient comprising administering to the patient (i) an antibody having the ability of binding to CLDN18.2 and (ii) an agent stabilizing or increasing expression of CLDN18.2. |
| 地址 |
Mainz DE |
