| 发明名称 |
Small Molecule Ice Recrystallization Inhibitors And Methods Of Use Thereof |
| 摘要 |
Ice recrystallization inhibitor (IRI) compounds and methods for cryopreserving umbilical cord blood are provided. The compounds are unsubstituted, mono-substituted, or di-substituted aryl-adlonamides. The methods include fractionating whole umbilical cord blood to generate a fraction comprising hematopoietic stem cells, mixing the hematopoietic stem cells with at least one IRI compound to form an IRI suspension, and freezing the IRI suspension. |
| 申请公布号 |
US2015373968(A1) |
申请公布日期 |
2015.12.31 |
| 申请号 |
US201514848942 |
申请日期 |
2015.09.09 |
| 申请人 |
THE UNIVERSITY OF OTTAWA |
发明人 |
BEN Robert;CAPICCIOTTI Chantelle J.;Briard Jennie |
| 分类号 |
A01N1/02 |
主分类号 |
A01N1/02 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
1. A composition for cryopreserving umbilical cord blood, the composition comprising:
at least one ice recrystallization inhibitor (IRI) compound, wherein the IRI is a benzyl-aldonamide. |
| 地址 |
Ottawa CA |
