Treatment of diabetic patients with a drug eluting stent and adjunctive therapy

摘要

Embodiments of the present invention include methods for the treatment, prevention, or amelioration of vascular disease in diabetic patients. The methods include both implantation of a stent including a first drug. Some embodiments include additional therapy, such as the co-administration of another drug. Some embodiments involve different stent selection for a diabetic patient compared to a non-diabetic patient.

主权项

1. A method of treating, preventing, or ameliorating a vascular disease in a diabetic patient, the method comprising:
implanting a stent comprising a first drug in a vascular region of a diabetic patient; and administering a second drug to the diabetic patient via transdermal administration; wherein the first drug is an anti-inflammatory, an antiproliferative, an antineoplastic, an antimitotic, an antiplatelet, an anticoagulant, an antifibrin, an antithrombin, an antibiotic, an anti-allergic, an antioxidant substance, or any combination thereof; and wherein the second drug reduces platelet activation, reduces tissue factor activity, reduces thrombin activity, or any combination thereof.