发明名称 PLATELET BIOMARKERS IN CANCER DIAGNOSIS
摘要 The present embodiments relate generally to the field of cancer diagnostics. More specifically the embodiments relate to platelet derived biomarkers used for diagnosis of cancer or cancer progression, as well as prognosis and improved treatment.
申请公布号 US2015369817(A1) 申请公布日期 2015.12.24
申请号 US201414762394 申请日期 2014.01.22
申请人 NEOPROTEOMICS AB 发明人 FRANZÈN Bo;AUER Gert;BECKER Susanne;LOMNYTSKA Marta;GEMOLL Timo;HABERMANN Jens
分类号 G01N33/68;G01N33/574 主分类号 G01N33/68
代理机构 代理人
主权项 1. A method of determining whether a subject is suffering from a benign lesion or from a carcinoma lesion, said method comprising: measuring at least two platelet-derived biomarkers in a biological sample from said subject, wherein said at least two platelet derived biomarkers are selected from a group consisting of α-actinin 1 (ACTN1), α-actinin 4 (ACTN4), crk-like protein (CRKL), endoplasmic reticulum protein 29 (ERP29), (FERM), fibrinogen gamma chain (FIBG), filamin A (FLNA), gelsolin (GELS), mitochondrial stress-70 protein (GRP75), HP protein, heat shock protein 70 kDa (HSP70), heat shock protein 71 kDa (HSP71), integrin alpha-2b (ITGA2B), integrin beta-3 (ITB3), ribonuclease inhibitor (RINI), proto-oncogene tyrosine-protein kinase Src (SRC), tubulin (TBA), tubulin alpha-4A chain (TBA4A), 3-mercaptopyruvate sulfurtransferase (THTM), talin-1 (TLN1), tubulin beta-1 chain (TUBB1), vinculin (VCL) and WD repeat containing protein 1 (WDR1); and determining whether said subject is suffering from said benign lesion or from said carcinoma lesion based on said measurement.
地址 Stockholm SE