主权项 |
1. A method of determining whether a subject is suffering from a benign lesion or from a carcinoma lesion, said method comprising:
measuring at least two platelet-derived biomarkers in a biological sample from said subject, wherein said at least two platelet derived biomarkers are selected from a group consisting of α-actinin 1 (ACTN1), α-actinin 4 (ACTN4), crk-like protein (CRKL), endoplasmic reticulum protein 29 (ERP29), (FERM), fibrinogen gamma chain (FIBG), filamin A (FLNA), gelsolin (GELS), mitochondrial stress-70 protein (GRP75), HP protein, heat shock protein 70 kDa (HSP70), heat shock protein 71 kDa (HSP71), integrin alpha-2b (ITGA2B), integrin beta-3 (ITB3), ribonuclease inhibitor (RINI), proto-oncogene tyrosine-protein kinase Src (SRC), tubulin (TBA), tubulin alpha-4A chain (TBA4A), 3-mercaptopyruvate sulfurtransferase (THTM), talin-1 (TLN1), tubulin beta-1 chain (TUBB1), vinculin (VCL) and WD repeat containing protein 1 (WDR1); and determining whether said subject is suffering from said benign lesion or from said carcinoma lesion based on said measurement. |