Paper-Based Chemical Assay Devices With Improved Fluidic Structures

摘要

A chemical assay device includes a hydrophilic substrate and one or more hydrophobic structures that extend from a first side of the hydrophilic substrate to a second side of the hydrophilic substrate. A hydrophobic structure in the hydrophilic substrate forms a fluid barrier wall that extends from the first side of the hydrophilic substrate to the second side of the hydrophilic substrate with a deviation of less than 20° from a perpendicular axis between the first side and the second side.

主权项

1. A chemical assay device comprising:
a first hydrophilic substrate, the first hydrophilic substrate having a first side and a second side, a predetermined length and width, and a thickness of not more than 1 millimeter; and a first hydrophobic structure formed in the first hydrophilic substrate from a hydrophobic material and penetrating through substantially the thickness of the first hydrophilic substrate from the first side to the second side, the first hydrophobic structure forming a fluid barrier wall in the first hydrophilic substrate with a surface of the fluid barrier wall extending through the thickness of the first hydrophilic substrate with a deviation from perpendicular of less than 20° from the first side and second side of the first hydrophilic substrate.