| 发明名称 |
ENHANCING D-XYLOSE AND L-ARABINOSE UTILIZATION IN ZYMOMONAS CELLS |
| 摘要 |
Disrupting expression of a protein encoded by the region of the Zymomonas genome called ZMO0353 in the genomic sequence of the ZM4 strain was found to improve the use of xylose in a recombinant xylose utilizing Zymomonas cell. In addition, utilization of both xylose and arabinose was improved in a xylose and arabinose utilizing Zymomonas cell with this disruption, and increased ethanol production was achieved. |
| 申请公布号 |
US2015368674(A1) |
申请公布日期 |
2015.12.24 |
| 申请号 |
US201414312725 |
申请日期 |
2014.06.24 |
| 申请人 |
E I DU PONT DE NEMOURS AND COMPANY |
发明人 |
ELIOT ANDREW C;Tao Luan;Viitanen Paul V |
| 分类号 |
C12P7/06 |
主分类号 |
C12P7/06 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
1. A recombinant D-xylose utilizing Zymomonas cell comprising at least one genetic modification of an endogenous gene comprising a coding region having nucleotide sequence identity of at least 95% to SEQ ID NO:1, wherein expression of a functional protein by the gene is disrupted and wherein xylose utilization is increased as compared to D-xylose utilization in a cell that is identical except for lacking the genetic modification. |
| 地址 |
Wilmington DE US |
