发明名称 |
Prevention of Obesity in Antipsychotic, Antidepressant and Antiepileptic Medication |
摘要 |
O-(3-piperidino-2-hydroxypropyl)-nicotinic amidoxime or a pharmaceutically suitable acid addition salt thereof (BGP-15) can be used for the prevention or reduction of weight gain or obesity in a patient treated with an antipsychotic drug or an antidepressant drug or an antiepileptic drug. |
申请公布号 |
US2015366852(A1) |
申请公布日期 |
2015.12.24 |
申请号 |
US201514748150 |
申请日期 |
2015.06.23 |
申请人 |
N-Gene Research Laboratories, Inc. |
发明人 |
Nagy Peter Literati;Roth Jesse;Szilvassy Zoltan;Tory Kalman;Brownstein Michael;Takács Kálmán;Vigh Laszlo;Mandl József;Sümegi Balázs;Bernath Sandor;Kolonics Attila;Balogh Gábor;Egri Janos |
分类号 |
A61K31/4545;A61K45/06 |
主分类号 |
A61K31/4545 |
代理机构 |
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代理人 |
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主权项 |
1. A method for preventing or reducing the side effect leading to weight gain or obesity in a patient requiring a treatment with an antipsychotic antidepressant or antiepileptic drug comprising administering an effective amount of a known antipsychotic, antidepressant or antiepileptic drug and an effective non-toxic amount of O-(3-piperidino-2-hydroxy-1-propyl)-nicotinic amidoxime or a pharmaceutically acceptable acid addition salt thereof to the patient, wherein the administration of the O-(3-piperidino-2-hydroxy-1-propyl)-nicotinic amidoxime or a pharmaceutically acceptable acid addition salt thereof prevents or reduces the metabolic side-effect experienced by the patient requiring treatment with an antipsychotic, antidepressant or antiepileptic drug. |
地址 |
New York NY US |