| 发明名称 |
METHODS FOR ENHANCING AN IMMUNE RESPONSE TO AN ANTIGEN |
| 摘要 |
Provided are methods and kits for enhancing an immune response to an antigen in an individual comprising administering to the individual an effective amount of (a) LT-IIb or (b) LT-IIb(T13I) enterotoxin, and (c) an antigen, whereby the LT-IIb or LT-IIb(T13I) enterotoxin acts as an adjuvant to enhance the generation of antigen specific neutralizing antibodies. |
| 申请公布号 |
US2015366963(A1) |
申请公布日期 |
2015.12.24 |
| 申请号 |
US201414766047 |
申请日期 |
2014.02.06 |
| 申请人 |
THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK ;HEALTH RESEARCH, INC. |
发明人 |
CONNELL Terry D.;MANTIS Nicholas;GREENE Christopher |
| 分类号 |
A61K39/39 |
主分类号 |
A61K39/39 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
1. A method for enhancing an immune response to an antigen in an individual comprising administering intradermally to the individual a composition comprising an effective amount of:
(a) LT-IIb(T13I) enterotoxin, and (b) a toxin, wherein the resulting immune response is enriched for toxin neutralizing antibodies. |
| 地址 |
Amherst NY US |
