Uterine lavage for embryo retrieval

摘要

A device for recovering one or more blastocysts from the uterus of a human includes an outer guide member for insertion into a cervical canal of the human. The outer guide member includes a distal portion with an activatable seal for isolating the uterus from the external environment and defines a lumen having a longitudinal axis. The device also includes an inner catheter located within the lumen and slidable along the longitudinal axis of the lumen relative to the outer guide member. The inner catheter has a distal tip positionable distally of the seal to extend into the uterus and includes a fluid delivery lumen terminating at a distal fluid delivery port for delivering fluid into the uterus. The device defines a distal suction port for aspirating fluid and entrained blastocysts from the uterus. The distal fluid delivery port and the distal suction port are arranged such that, in use, fluid delivered from the distal fluid delivery port travels through the distal suction port to the uterus.

主权项

1. A process for recovering one or more blastocysts from the uterus of a human, comprising:
placing a device trans-vaginally into the cervical canal; and cyclically delivering fluid through the device to the uterus in at least two cycles wherein
the first cycle comprises delivering a first amount of fluid to form a first puddle encompassing the one or more blastocysts and applying a vacuum to the uterus to aspirate fluid and entrained blastocysts within the first puddle from the uterus; andthe second cycle comprises delivering a larger amount of fluid into the uterus to form a second, larger puddle and applying a vacuum to the uterus to aspirate fluid from the uterus, wherein a fluid delivery port for delivering fluid into the uterus and a suction port for aspirating fluid and entrained blastocysts from the uterus are provided such that in use fluid is deliverable from the fluid delivery port to travel through the suction port to the uterus.