| 主权项 |
1. A compound with the structure of Formula (XVII): wherein R6, R6′, R7, R7′, R8, R8′, R9, R9′ and R10 are independently selected from at least one of hydro, hydroxyl, halo, alkyl, alkoxy, haloalkyl, haloalkoxy, —N(C1-3 alkyl)2, —NH(C1-3 alkyl), —C(═O)NH2, —C(═O)NH(C1-3 alkyl), —C(═O)N(C1-3 alkyl)2, —S(═O)2(C1-3 alkyl), —S(═O)2NH2, —S(═O)2N(C1-3 alkyl)2, —S(═O)2NH(C1-3 alkyl), —CHF2, —OCF3, —OCHF2, —SCF3, —CF3, —CN, —NH2, and —NO2; R20 is aryl or heteroaryl; and R21 is heteroaryl; or a pharmaceutically-acceptable salt thereof, with the proviso that when R6, R6′, R7, R7′, R8, R8′, R9, R9′ and R10 are all hydro and R20 is unsubstituted phenyl, the compound is not 2-phenyl-1-(pyridin-3-yl)-4,5,6,7-tetrahydro-1H-indole; and with the proviso that when R9 is OH, R9′ is hydro, R7 and R7′ are each methyl, and the compound is not 6,6-dimethyl-2-phenyl-1-(pyridin-3-yl)-4,5,6,7-tetrahydro-1H-indol-4-ol. |
