ACYLATED INSULIN ANALOGUES STABILISED WITH RESPECT TO PROTEASES

摘要

FIELD: medicine, pharmaceutics.SUBSTANCE: invention relates to biochemistry. Described is acylated, stabilised with respect to proteases insulin. Application of the described insulin for the production of a pharmaceutical composition for the treatment or prevention of hyperglycaemia, type 2 diabetes mellitus, impaired tolerance to glucose and type 1 diabetes mellitus is presented.EFFECT: invention makes it possible to obtain the insulin analogues, stable to proteases.24 cl, 11 dwg, 1 tbl, 184 ex