发明名称 SARM COMPOUNDS AND METHODS OF THEIR APPLICATION
摘要 FIELD: medicine, pharmaceutics.SUBSTANCE: claimed invention relates to methods of influencing composition of animal carcass by introduction of acylanilide compounds of selective androgenic receptor modulators (SARM), represented by formula, where Z stands for NO, CN, Cl, F, Br or I; Y stands for CF, F, Br, Cl or I; Rstands for H, F, Cl, Br, I, CH, CF, OH, CN, NO, NHCOCHor NHCOCF; Rstands for H; Q stands for H, halogen, CFor CN; n=1; and m=1; or its isomer, pharmaceutically acceptable salt, crystal, N-oxide, hydrate or any their combination, where composition of carcass is subjected to impact by increase of fat-free mass, reduction of fat mass and/or reduction of percentage of fat mass; and where animals are represented by feedlot animals, beef cattle or fattening cattle. Impact on carcass composition in animals includes increase of growth indices, increase of average day gain (ADG) and increase of ratio forage:gain (F:G). Method includes feeding animals with such everyday forage, which contains formula IIIA compound.EFFECT: improvement of meat production in fattening animals by increase of fat-free mass, reduction of fat mass and/or reduction of percentage of fat mass, increase of forage effectiveness and modulation of meat quality in animals, in feedlot animals or fattening cattle of beef cattle type or pigs.13 cl, 26 dwg, 11 tbl, 20 ex
申请公布号 RU2571421(C2) 申请公布日期 2015.12.20
申请号 RU20120144842 申请日期 2011.03.22
申请人 JUNIVERSITI OF TENNESSI RISERCH FAUNDEJSHN 发明人 DOLTON DZHEJMS T.;MILLER DUEHJN D.;KIRBI DZHEFFRI
分类号 C07C255/60;A23K1/22;A61K31/167;C07C235/24 主分类号 C07C255/60
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