SELF MICRO-EMULSIFYING ORAL PHARMACEUTICAL COMPOSITION OF HYDROPHILIC DRUG AND PREPARATION METHOD THEREOF

摘要

A self micro-emulsifying oral pharmaceutical composition of a hydrophilic drug or its pharmaceutical acceptable salt and the preparation method thereof are disclosed. The composition comprises hydrophilic drug such as bendamustine or gemcitabine, solvent, surfactant and hydrophilic carrier, and has good bioavailability and stability. Said hydrophilic carrier is compatible with drug solution and surfactant.