发明名称 GLA Monotherapy for Use in Cancer Treatment
摘要 The present disclosure relates generally to compositions and methods for treating cancer with a glucopyranosyl lipid A (GLA) in the absence of antigen.
申请公布号 US2015359811(A1) 申请公布日期 2015.12.17
申请号 US201514836115 申请日期 2015.08.26
申请人 IMMUNE DESIGN CORP. 发明人 Paya Cuenca Carlos V.;Ter Meulen Jan Henrik
分类号 A61K31/7016;A61K39/395;A61K45/06 主分类号 A61K31/7016
代理机构 代理人
主权项 1. A method of treating a mammal who suffers from cancer, comprising administering an effective amount of a composition comprising GLA, said composition comprising: (a) GLA of the formula: wherein: R1, R3, R5 and R6 are C11-C20 alkyl; and R2 and R4 are C12-C20 alkyl; and (b) a pharmaceutically acceptable carrier or excipient; wherein the composition does not comprise antigen.
地址 Seattle WA US