发明名称 |
GLA Monotherapy for Use in Cancer Treatment |
摘要 |
The present disclosure relates generally to compositions and methods for treating cancer with a glucopyranosyl lipid A (GLA) in the absence of antigen. |
申请公布号 |
US2015359811(A1) |
申请公布日期 |
2015.12.17 |
申请号 |
US201514836115 |
申请日期 |
2015.08.26 |
申请人 |
IMMUNE DESIGN CORP. |
发明人 |
Paya Cuenca Carlos V.;Ter Meulen Jan Henrik |
分类号 |
A61K31/7016;A61K39/395;A61K45/06 |
主分类号 |
A61K31/7016 |
代理机构 |
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代理人 |
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主权项 |
1. A method of treating a mammal who suffers from cancer, comprising administering an effective amount of a composition comprising GLA, said composition comprising:
(a) GLA of the formula: wherein: R1, R3, R5 and R6 are C11-C20 alkyl; and R2 and R4 are C12-C20 alkyl; and (b) a pharmaceutically acceptable carrier or excipient; wherein the composition does not comprise antigen. |
地址 |
Seattle WA US |