发明名称 |
Process for preparing oxycodone hydrochloride having less than 25 ppm 14-hydroxycodeinone |
摘要 |
<p>PROCESS FOR PREPARING OXYCODONE HYDROCHLORIDE HAVING LESS THAN 25 PPM 14-HYDROXYCODEINONE Abstract Oxycodone is a semi-synthetic opioid analgesic that exerts an agonist effect at specific, saturatable opioid receptors in the CNS and other tissues. 14-hydroxycodeinone is an impurity formed in the production of oxycodone from thebaine. The invention provides a purified oxycodone hydrochloride having less than 25 ppm 14-hydroxycodeinone and processes for its production.</p> |
申请公布号 |
AU2015261590(A1) |
申请公布日期 |
2015.12.17 |
申请号 |
AU20150261590 |
申请日期 |
2015.11.25 |
申请人 |
PURDUE PHARMA L.P. |
发明人 |
CHAPMAN, ROBERT;RIDER, LONN S.;HONG, QI;KYLE, DONALD;KUPPER, ROBERT |
分类号 |
C07D489/00;A61K31/485;C07D489/08 |
主分类号 |
C07D489/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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