LOW SWELL TISSUE ADHESIVE AND SEALANT FORMULATIONS
摘要
A hydrogel tissue adhesive formed by reacting an aldehyde-functionalized dextran containing pendant aldehyde groups with a multi-arm polyethylene glycol amine is described. The hydrogel exhibits little to no swell upon exposure to physiological conditions. The hydrogel may be useful as a tissue adhesive or sealant for medical applications that require a low swell hydrogel to inhibit complications, such as fibrosis, including scar formation or surgical adhesions.
申请公布号
WO2015017340(A3)
申请公布日期
2015.12.17
申请号
WO2014US48459
申请日期
2014.07.28
申请人
ACTAMAX SURGICAL MATERIALS, LLC;JENKINS, LAURI, L.;DILUCCIO, ROBERT, C.