Processes for Making Magnolol Derivatives

摘要

Described herein are high yield methods for making magnolol derivatives, together with novel intermediates and uses thereof.

主权项

1. A method for making 3,3′-diallyl-biphenyl-2,2′-diol or 3,3′-dipropyl-biphenyl-2,2′-diol, comprising heating neat 2,2′-di(allyloxy)-biphenyt at a temperature of 200-220° C. for a period of at least four hours until it is substantially converted to 3,3′-diallyl-biphenyl-2,2′-diol, and optionally hydrogenating the 3,3′-diallyl-biphenyl-2,2′-diol to obtain 3,3 ′-dipropyi-biphenyl-2,2 -diol.