SPECIFIC PROTEIN MARKER AND METHOD FOR IDENTIFYING THE STATISTIC DISTRIBUTION OF PROTEIN STOICHIOMETRY

摘要

The present invention relates to a specific protein marker and to a method for identifying the statistic distribution of protein stoichiometry. New specific protein markers and methods for detecting the markers need to be developed for clarifying important biological questions. The problem is solved by a specific protein marker, the specific protein marker comprising two (separate) units, of which the first unit comprises a molecule for specifically binding to a protein and at least one chemically coupled molecule for binding to the second unit, and the second unit comprises a surface-modified nanoparticle, and the surface-modified nanoparticle comprises a surface coating comprising at least one molecule for binding to the first unit.