发明名称 |
ARYL-SULPHONAMIDIC DIMERS AS METALLOPROTEASES INHIBITORS |
摘要 |
<p>The invention relates to dimeric aryl-sulphonamido compounds endowed with inhibitory activity against metalloproteases MMP, having formula (I) below (M)-L-(M') (I), wherein M and M', the same or different from each other, represent the residues of the metalloproteases inhibitors of formula (II), wherein R, R1, R2, R3, G and n have the meanings reported in the specification; the invention also refers to the process for their preparation, to pharmaceutical compositions comprising them and to their use as therapeutic agents, particularly in the treatment of degenerative disorders.</p> |
申请公布号 |
WO2010010080(A1) |
申请公布日期 |
2010.01.28 |
申请号 |
WO2009EP59339 |
申请日期 |
2009.07.21 |
申请人 |
BRACCO IMAGING SPA;ROSSELLO, ARMANDO;NUTI, ELISA;TUCCINARDI, TIZIANO;ORLANDINI, ELISABETTA |
发明人 |
ROSSELLO, ARMANDO;NUTI, ELISA;TUCCINARDI, TIZIANO;ORLANDINI, ELISABETTA |
分类号 |
C07D295/205;A61K31/496;A61P25/00;C07C311/00 |
主分类号 |
C07D295/205 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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