METHOD FOR FOLLOWING UP THE CRYSTALLISATION OF A SUBSTANCE, AND CORRESPONDING MICROFLUIDIC DEVICE AND SCREENING METHOD

摘要

The crystallization of chemical species/polymorphs comprises forming droplets of a solution of a substance with optionally different concentrations of said substance in an inert phase; producing and storing the droplets in at least one storage microchannel (1); forming crystals in all droplets; increasing the temperature in order to induce the dissolution of at least a portion of the crystals in at least some droplets; and analyzing the crystallization and dissolution process.