发明名称 |
Methods for a predictive diagnostic test for tamoxifen |
摘要 |
A method for determining the likelihood that a therapy involving administration of tamoxifen to a patient afflicted with an estrogen receptor positive breast cancer will provide a therapeutic benefit to the patient which comprises determining the level of expression of epidermal growth factor receptor present within a non-nuclear compartment in cells present in a breast tissue sample from the patient; and comparing the level of expression so obtained to a predetermined level of expression wherein the likelihood the therapy will provide a therapeutic benefit to the patient is greater if the level of expression in step a) is less than the predetermined level of expression.
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申请公布号 |
US2009155767(A1) |
申请公布日期 |
2009.06.18 |
申请号 |
US20080215458 |
申请日期 |
2008.06.27 |
申请人 |
RIMM DAVID L;GILTNANE JENNIFER M;RYDEN LISA |
发明人 |
RIMM DAVID L.;GILTNANE JENNIFER M.;RYDEN LISA |
分类号 |
C12Q1/00 |
主分类号 |
C12Q1/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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