| 发明名称 |
HIGH PRESSURE REFOLDING OF MONOCLONAL ANTIBODY AGGREGATES |
| 摘要 |
Methods for refolding antibodies, particularly monoclonal antibodies, from aggregated and/or denatured preparations by subjecting the antibody preparation to high hydrostatic pressure are provided. Refolded preparations of antibodies produced by the methods described herein are also provided.
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| 申请公布号 |
US2009076247(A1) |
申请公布日期 |
2009.03.19 |
| 申请号 |
US20080208193 |
申请日期 |
2008.09.10 |
| 申请人 |
SEEFELDT MATTHEW B;NELSON ROBERT;RANDOLPH THEODORE W;HESTERBERG LYNDAL K |
发明人 |
SEEFELDT MATTHEW B.;NELSON ROBERT;RANDOLPH THEODORE W.;HESTERBERG LYNDAL K. |
| 分类号 |
C07K16/00;C07K19/00;G01J3/00;G01N21/00;G01N33/536;G01T1/10;G01V3/00 |
主分类号 |
C07K16/00 |
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