发明名称 USE OF GILZ PROTEIN EXPRESSED IN DENDRITIC CELLS TO MODULATE AN ANTIGEN-SPECIFIC IMMUNE RESPONSE
摘要 The invention concerns the use of at least one: a) a GILZ protein, a functional fragment of at least 5 consecutive amino acids of said protein, a GILZ modulator, or a recombinant vector expressing same, isolated or expressed in modified dendritic cells, and b) an antigen of interest and/or a molecule allowing targeting and/or passage of the plasmic membrane of dendritic cells, to prepare a medicine for preventing and/or treating autoimmune, inflammatory diseases, allergies, graft rejection and graft-versus-host disease, cancers and pathogenic micro-organism infections.
申请公布号 US2009028875(A1) 申请公布日期 2009.01.29
申请号 US20050575073 申请日期 2005.09.09
申请人 ASSISTANCE PUBLIQUE-HOPITAUX DE PARIS 发明人 EMILIE DOMINIQUE;COHEN NICOLAS;LEMOINE FRANCOIS
分类号 A61K35/30;A61K31/7088;A61K31/7105;A61K38/08;A61K38/10;A61K38/16;A61K38/17;A61K39/00;A61K39/395;A61K48/00;A61P29/00;A61P37/00;A61P37/08;C12N5/0783;C12N5/0784;C12N5/10;C12N15/113 主分类号 A61K35/30
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