发明名称 Pegylierte Single-domain-antikörper (dAb)
摘要 Disclosed is a PEG-linked polypeptide comprising an antibody single variable domain, wherein the variable domain comprises a framework region and has an antigen binding site, and said variable domain binds antigen as a single antibody variable domain in the polypeptide, and further wherein said PEG is present as one or more molecules linked to the polypeptide at a cysteine or lysine residue in the framework regions of said antibody single variable domain.
申请公布号 DE602004017726(D1) 申请公布日期 2008.12.24
申请号 DE20046017726T 申请日期 2004.06.30
申请人 DOMANTIS LTD. 发明人 BASRAN
分类号 C07K16/24;A61K47/48;C07K16/00;C07K16/18;C07K16/28;C07K16/40;C07K16/46;C12N15/13 主分类号 C07K16/24
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