| 发明名称 |
Chimeric Transcription Factor Decoy Oligonucleotides |
| 摘要 |
A method for the treatment of the brain cancer glioblastoma multiforme (GBM) is provided. The method involves decreasing the expression of Matrix Metalloproteinase-1 (MMP-1) expression by providing transcription factor decoy nucleotides that mimic single nucleotide polymorphisms responsible for MMP-1 overexpression.
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| 申请公布号 |
US2008233644(A1) |
申请公布日期 |
2008.09.25 |
| 申请号 |
US20040570160 |
申请日期 |
2004.09.10 |
| 申请人 |
FILLMORE HELEN;MARTIN REGE JESSICCA I |
发明人 |
FILLMORE HELEN;MARTIN REGE JESSICCA I. |
| 分类号 |
C12N5/02;A01N43/04;A61K;A61P35/00;C07H21/00;C07H21/04;C12N9/64;C12N15/113;C12N15/115 |
主分类号 |
C12N5/02 |
| 代理机构 |
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代理人 |
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