摘要 |
PROBLEM TO BE SOLVED: To provide a method for purifying alkylaminopyridines which can remove the impurities the separation of which by distillation has been difficult conventionally. SOLUTION: This method for purifying the alkylaminopyridines expressed by formula (2) prepared by the Hofmann degradation of an alkylpyridine carboxyamides expressed by formula (1) [wherein, R is a 1-6C alkyl] comprises mixing the alkylaminopyridines with an acid, to prepare acid salts of alkylaminopyridines, and then treating acid salts of the alkylaminopyridines with a base. COPYRIGHT: (C)2008,JPO&INPIT
|