发明名称 |
Method and medicament for inhibiting the expression of a given gene |
摘要 |
The present invention relates to the specific inhibition of expression of a target gene in mammals using a short double stranded RNA. The dsRNA is less than 49 nucleotides in length and has a nucleotide sequence which is complementary to at least a part of the target gene. The dsRNAs of the present invention are useful for treating diseases, for example, cancer, viral diseases or neurodegenerative diseases.
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申请公布号 |
US2008233651(A1) |
申请公布日期 |
2008.09.25 |
申请号 |
US20070982434 |
申请日期 |
2007.10.31 |
申请人 |
KREUTZER ROLAND;LIMMER STEFAN |
发明人 |
KREUTZER ROLAND;LIMMER STEFAN |
分类号 |
C12N15/09;A61K9/127;A61K31/70;A61K31/713;A61K35/76;A61K38/00;A61K47/48;A61K48/00;A61P25/28;A61P31/12;A61P35/00;C12N15/11 |
主分类号 |
C12N15/09 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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