发明名称 |
METHODS OF TREATING DISORDERS ASSOCIATED WITH FAT STORAGE |
摘要 |
The invention relates, in general, to markers of obesity and lipodystrophy. In particular, the expression level of the SLUG gene or its expression products can be used as such a marker. Furthermore, the invention additionally relates to the use of SLUG as a therapeutic and diagnostic target for these pathologies. The invention further relates to a method of treating a disorder associated with increased or decreased fat storage in a mammal comprising modulating the activity or level of the SLUG protein or the SLUG gene in the mammal. |
申请公布号 |
WO2008047235(A3) |
申请公布日期 |
2008.09.25 |
申请号 |
WO2007IB03736 |
申请日期 |
2007.09.24 |
申请人 |
UNIVERSIDAD DE SALAMANCA;CONSEJO SUPERIOR DE INVESTIGACIONES CIENTIFICAS;SANCHEZ-GARCIA, ISIDRO;PEREZ-MANCERA, PEDRO A |
发明人 |
SANCHEZ-GARCIA, ISIDRO;PEREZ-MANCERA, PEDRO A |
分类号 |
A61K39/00 |
主分类号 |
A61K39/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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