| 摘要 |
2-Nitroimidazole derivatives (I) and their salts. where R1 and R2 = H or alkyl (1-7C) or when at least one of R1 and R2 = alkyl, or when R1=R2=H R3 = H, halogen, OH, alkoxy, alkenyloxy, alkynyloxy, haloalkoxy, polyhaloalkoxy, haloalkynyloxy, phenoxy opt. subst, by halogen, alkyl or alkoxy. Ac = alkanoyl, or benzoyl opt. substd. by halogen, alkyl or alkoxy. R4 = H or alkanoyl R31 = alkenyloxy, alkynyloxy, haloalkoxy, polyhaloalkoxy, haloalkynyloxy, or phenoxy opt. subst. by halogen, alkyl or alkoxy R32 = R3 except it cannot represent H Ac1 = benzoyl opt. subst. by halogen, alkyl or alkoxy. Alkoxy etc. gps. contain up to 7 C atoms. - Antimicrobial agents, active against bacteria, fungi, pathogenic yeasts and protozoa e.g. Trichomonas vaginalis, Trichomonas foetus, Histomonas meleagridis, Endamoeba histolytica, Trypanosomes, e.g. T.cruzi, T.rhodesiense, T.congolense etc.
|
