POLYNUCLEOTIDE ENCODING HUMAN-TYPE FC RECEPTOR, AND METHOD FOR PRODUCTION OF HUMAN-TYPE FC RECEPTOR UTILIZING THE SAME

摘要

The object is to produce a microorganism which can produce a human-type Fc receptor Fc?RI on an industrial scale, to produce the human-type Fc?RI by utilizing the novel Fc receptor production system, and to provide the Fc?RI. A polynucleotide encoding Bacillus bacterium-type Fc?RI is prepared by modifying the codons of a polynucleotide encoding human-type Fc?RI into codons of the Bacillus bacterium type one. A Bacillus bacterium is transformed with a plasmid vector having the polynucleotide encoding the Bacillus bacterium-type Fc?RI introduced therein. In this manner, human-type Fc?RI can be expressed in a large quantity without the need of carrying out solubilization or the like.