COMPOUND HAVING 6-MEMBERED AROMATIC RING

摘要

Disclosed is a prophylactic or therapeutic agent for schizophrenia or the like, which has a GPR52 agonistic activity. Specifically disclosed is a compound represented by formula (I) or a salt thereof. In formula (I), A represents -(CH2)n-CO-NRa- (wherein n represents an integer of 0 to 3) or -NRa-CO-; B represents a hydrogen atom, a halogen atom, a cyano group, a hydroxy group or the like; X1, X2, X3 and X4 independently represent -CRx= or -N=; Y represents -O-, -S-, -S(O)-, -S(O)2- or -NRy-; Z represents a bond, a methylene or an ethylene; Ar1 represents a 5- to 10-membered aromatic ring (excluding a thiazole) which may be substituted by at least one substituent selected from a halogen atom, an optionally halogenated C1-6 alkyl group and the like; Ar2 represents a 5- to 6-membered aromatic ring which may be substituted by at least one substituent selected from a halogen atom, an optionally halogenated C1-6 alkyl group and the like and which may be fused with an optionaly substituted 5- to 6-membered ring; and Ra, Rb, Rx and Ry independently represent a hydrogen atom, a halogen atom or the like.