发明名称 TRICYCLIC ORGANIC MONOPEROXIDES AND METHOD FOR PREPARING THEM
摘要 FIELD: medicine, pharmaceutics. ^ SUBSTANCE: present invention refers to chemistry of organic peroxides, ketone derivatives, more specifically to a new class of tricyclic organic mononperoxides of general formula I: wherein R1 = alkyl or 4-methoxyphenyl; R2 = hydrogen, benzyl, unsubstituted or substituted alkyl with the substitutes presented by CN or COOR3, wherein R3 = alkyl, and to a method for preparing them consisting in a reaction of ,-triketones of general formula II: wherein R1 and R2 have the values specified above, and hydrogen peroxide in the presence of boron trifluoride in a medium of diethyl ester. The prepared compounds contain one O-O fragment, one acetal and two monoperoxideacetal fragments. They can find application as initiators for radical polymerisation of unsaturated monomers, as well as in medicine and pharmacology as antiparasitic agents. ^ EFFECT: preparing the compounds which can find application as initiators for radical polymerisation of unsaturated monomers, as well as in medicine and pharmacology as antiparasitic agents. ^ 3 cl, 4 ex
申请公布号 RU2466133(C1) 申请公布日期 2012.11.10
申请号 RU20110125815 申请日期 2011.06.24
申请人 FEDERAL'NOE GOSUDARSTVENNOE BJUDZHETNOE UCHREZHDENIE NAUKI INSTITUT ORGANICHESKOJ KHIMII IM. N.D. ZELINSKOGO ROSSIJSKOJ AKADEMII NAUK (IOKH RAN) 发明人 TERENT'EV ALEKSANDR OLEGOVICH;JAREMENKO IVAN ANDREEVICH;NIKISHIN GENNADIJ IVANOVICH
分类号 C07D493/18 主分类号 C07D493/18
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