发明名称 METHOD FOR PREDICTION OF CERVICAL CANCER IN BENIGN AND PRE-CANCER CERVICAL PROCESSES IN FEMALES OF REPRODUCTIVE AGE
摘要 FIELD: medicine. ^ SUBSTANCE: invention refers to a method for prediction of cervical cancer in benign and pre-cancer cervical processes in females of reproductive age involving description of clinical risk factors of developing cervical cancer, MLH1, HIC1, RASSF1A, MGMT, N33, CDH1 gene methylation in a cervical biopsy material and calculation of a probability coefficient of developing cervical cancer p. If the value p is more than 0.6, a high probability of developing cervical cancer is predicted, the value p equal to 0.3-0.59 enables predicting a moderate probability of developing cervical cancer, and if the value p is less than 0.29, a low probability of developing cervical cancer is predicted. ^ EFFECT: method provides more accurate prediction of cervical cancer in benign and pre-cancer cervical diseases in females of reproductive age. ^ 2 ex
申请公布号 RU2466392(C2) 申请公布日期 2012.11.10
申请号 RU20110105302 申请日期 2011.02.15
申请人 GOSUDARSTVENNOE OBRAZOVATEL'NOE UCHREZHDENIE VYSSHEGO PROFESSIONAL'NOGO OBRAZOVANIJA PERVYJ MOSKOVSKIJ GOSUDARSTVENNYJ MEDITSINSKIJ UNIVERSITET IM. I.M. SECHENOVA MINISTERSTVA ZDRAVOOKHRANENIJA I SOTSIAL'NOGO RAZVITIJA ROSSIJSKOJ FEDERATSII (GOU VPO 发明人 SIDOROVA IRAIDA STEPANOVNA;UNANJAN ARA LEONIDOVICH;EVTINA IRINA PAVLOVNA;ZALETAEV DMITRIJ VLADIMIROVICH
分类号 A61B10/02;G01N33/48 主分类号 A61B10/02
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