AQUEOUS DISPERSION OF CHEMILUMINESCENT NANOPARTICLES, AND PREPARATION METHOD AND USE THEREOF

摘要

PURPOSE: Aqueous-dispersed chemical-luminescent nanoparticles, a producing method thereof, and a use thereof are provided to accurately and extensively diagnose active oxygen related disease by directly imaging hydrogen peroxide. CONSTITUTION: Aqueous-dispersed chemical-luminescent nanoparticles contain the following: 0.01~3wt% of core containing a hydrophobic chemical-luminescent substance; 0.5~30wt% of surfactant surrounding the core; and 67~99.49wt% water. The luminescent wavelength of the hydrophobic chemical-luminescent substance is 650~900nm. The hydrophobic chemical-luminescent substance is formed with a peroxyoxalate derivative and a fluorescent material. The surfactant is poloxamer.