发明名称 Novel fluorescent near-infrared (NIR) dyes
摘要 A compound of formula (I) is described in which each A, which may be the same or different, is a halide selected from fluoride, chloride, bromide and iodide, or is O-Y, wherein Y is a substituted or unsubstituted, saturated or unsaturated, straight or branched chain alkyl moiety. R1, R2, R3, R6, R7, AND R8 are each independently H, OH, NO2 or O-L-X, wherein L is a spacer group, and X is a conjugation group or a water-solubilizing group. At least on of R1, R2, R3 is OH or O-L-X and at least one of R6, R7 and R8 is OH or O-L-X. R4 and R5, which may be the same or different, are each independently H; or are a substituted, saturated or unsaturated, cyclic moiety; a substituted or unsubstituted, saturated or unsaturated heterocyclic moiety; or a substituted or unsubstituted, saturated or unsaturated, straight or branched chain alkyl moiety. Also described are dye conjugates comprising a compound of the invention.
申请公布号 IES20100683(A2) 申请公布日期 2011.06.08
申请号 IES20100683 申请日期 2010.10.22
申请人 HAE THERAPEUTICS 发明人 DONAL O'SHEA
分类号 C07F5/00 主分类号 C07F5/00
代理机构 代理人
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