| 发明名称 |
HYDROGEN HALIDES OF N-[2-(1ALKYL-1H-INDOL-3-LY)-1-(4-ALKYLPIPERAZINE-1-CARBONYL)-VINYL]-2-FLUOROBENZAMIDE, HAVING LOCAL ANAESTHETIC AND ANTIARHYTHMIC ACTIVITY |
| 摘要 |
FIELD: chemistry. ^ SUBSTANCE: invention relates to novel indole derivatives, specifically to hydrogen halides of N-[2-(1-alkyl-1H-indol-3-yl)-1-(4-alkylpiperazine-1-carbonyl)-vinyl]-2-fluorobenzamide of formula I: , where R1 and R2=alkyl C1-C6, X=Cl, Br, having local anaesthetic and antiarhythmic activity. ^ EFFECT: obtaining new indole derivatives having useful biological properties. ^ 11 tbl, 1 ex |
| 申请公布号 |
RU2408579(C2) |
申请公布日期 |
2011.01.10 |
| 申请号 |
RU20080153020 |
申请日期 |
2008.12.31 |
| 申请人 |
FEDERAL'NOE GOSUDARSTVENNOE OBRAZOVATEL'NOE UCHREZHDENIE VYSSHEGO PROFESSIONAL'NOGO OBRAZOVANIJA "JUZHNYJ FEDERAL'NYJ UNIVERSITET" (JUFU);GOSUDARSTVENNOE OBRAZOVATEL'NOE UCHREZHDENIE VYSSHEGO PROFESSIONAL'NOGO OBRAZOVANIJA "KUBANSKIJ GOSUDARSTVENNYJ MEDITSINSKIJ UNIVERSITET FEDERAL'NOGOAGENTSTVA PO ZDRAVOOKHRANENIJU I SOTSIAL'NOMU RAZVITIJU", (KGMI) |
发明人 |
SUZDALEV KONSTANTIN FILIPPOVICH;BABAKOVA MARIJA NIKOLAEVNA;GALENKO-JAROSHEVSKIJ PAVEL ALEKSANDROVICH;VARLASHKINA INESSA ALEKSANDROVNA;CHEREDNIK IRINA LEONIDOVNA;SHEJKH-ZADE JURIJ RESHADOVICH;TARAN OKSANA ANATOL'EVNA;TAKHCHIDI KHRISTO PERIKLOVICH;SAKHNOV SERGEJ NIKOLAEVICH;DOL'SKAJA OKSANA ALEKSANDROVNA;LISITSYNA NADEZHDA PAVLOVNA;BGUASHEVA BEHLLA ASKEROVNA;BOGUS SAIDA KAZBEKOVNA |
| 分类号 |
A61K31/404;A61P9/06;A61P23/02;C07D209/12;C07D403/06 |
主分类号 |
A61K31/404 |
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