摘要 |
<P>PROBLEM TO BE SOLVED: To solve the problem with the detection of hepatotoxicity using hematological or pathological techniques wherein it is hard to evaluate the detection because markers are limited. <P>SOLUTION: Since in vivo changes in gene expressions due to changes in external environments are acute, the identification of a gene set for determining biotoxicity makes it possible to quickly and precisely detect biotoxicity before the biotoxicity takes place and before it is verified by a pathological examination. A method of detecting and predicting biotoxicity using the new gene set, its kit, a method of treating biotoxicity, and a method of confirming candidate drugs for biotoxicity are provided. <P>COPYRIGHT: (C)2013,JPO&INPIT |