| 摘要 |
Disclosed is a compound which is useful as a therapeutic or prophylactic agent for diseases associated with 5-HT2C receptor, especially for urinary incontinence such as stress urinary incontinence, urge urinary incontinence and mixed urinary incontinence, sexual dysfunction such as erectile dysfunction, obesity and the like. Studies have been made on compounds which have a 5-HT2C receptor agonist action and are thus promising as active ingredients of pharmaceutical compositions for the treatment or prophylaxis of urinary incontinence such as stress urinary incontinence, urge urinary incontinence and mixed urinary incontinence, sexual dysfunction such as erectile dysfunction, obesity and the like, and it is confirmed that a specific benzazepine compound has an excellent 5-HT2C receptor agonist action. The benzazepine compound has a 5-HT2C receptor agonist action and can be used as a therapeutic or prophylactic agent for diseases associated with 5-HT2C receptor, especially for urinary incontinence such as stress urinary incontinence, urge urinary incontinence and mixed urinary incontinence, sexual dysfunction such as erectile dysfunction, obesity and the like. |
