发明名称 |
Method for amplifying variation of frequency of signal in piezoelectrical biosensor |
摘要 |
Provided is a method for amplifying a frequency variation of a detected signal in a biosensor that is used for detecting a biomolecule by measuring a change in frequency of an oscillating signal, the change being caused by pressure a biomolecule applies to a piezoelectric substance. The method for amplifying a frequency variation of a detected signal comprises the steps of: (a) applying a sample to a probe being fixed to an upper portion of a substrate of the biosensor to allow a biomolecule in the sample to be bound to the probe; (b) applying protein tagged with a metal particle to the biosensor to allow the protein and the biomolecule to be bound with each other; and (c) applying a metal enhancer to the biosensor to allow the metal enhancer to be bound to the metal particle having been bound to the protein.
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申请公布号 |
US8440468(B2) |
申请公布日期 |
2013.05.14 |
申请号 |
US20080099896 |
申请日期 |
2008.04.09 |
申请人 |
LEE HUN JOO;LEE SOO SUK;SAMSUNG ELECTRONICS CO., LTD. |
发明人 |
LEE HUN JOO;LEE SOO SUK |
分类号 |
G01N33/551 |
主分类号 |
G01N33/551 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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