| 发明名称 |
ANTI-SCLEROSTIN ANTIBODIES |
| 摘要 |
Humanized and chimeric antibodies are provided that specifically bind human sclerostin and are characterized as having high affinity and strong neutralizing properties. The antibodies of the invention are useful for increasing bone mass, bone mineral density and bone strength and for the treatment of various disorders, e.g., osteoporosis, in human subject. |
| 申请公布号 |
EA018204(B1) |
申请公布日期 |
2013.06.28 |
| 申请号 |
EA20090070874 |
申请日期 |
2008.03.11 |
| 申请人 |
ELI LILLY AND COMPANY |
发明人 |
KORYTKO ANDREW, IHOR;MARQUIS DAVID, MATTHEW;SMITH ERIC, MICHAEL;SWANSON BARBARA, ANNE |
| 分类号 |
A61K39/395;A61P19/00;A61P19/08;A61P19/10;C07K16/18 |
主分类号 |
A61K39/395 |
| 代理机构 |
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