发明名称 CYCLOPROPANEAMINE COMPOUND
摘要 The present invention provides a compound having a lysine-specific demethylase 1 inhibitory action, and useful as a medicament such as a prophylactic or therapeutic agent for cancer, and central nervous system diseases, and the like. The present invention relates to a compound represented by the formula wherein A is a hydrocarbon group or heterocyclic group optionally having substituent(s); R is H, a hydrocarbon group or heterocyclic group optionally having substituent(s); A and R are optionally bonded to each other to form a ring optionally having substituent(s); Q 1 , Q 2 , Q 3 and Q 4 are each a hydrogen atom or a substituent; Q 1 and Q 2 , and Q 3 and Q 4 , are each optionally bonded to each other to form a ring optionally having substituent(s); X is H, an acyclic hydrocarbon group or saturated cyclic group optionally having substituent(s); Y 1 , Y 2 and Y 3 are each H, a hydrocarbon group or heterocyclic group optionally having substituent(s); X and Y 1 , and Y 1 and Y 2 , are each optionally bonded to each other to form a ring optionally having substituent(s); and Z 1 , Z 2 and Z 3 are each H or a substituent, or a salt thereof.
申请公布号 KR20140052018(A) 申请公布日期 2014.05.02
申请号 KR20147006235 申请日期 2012.08.08
申请人 TAKEDA PHARMACEUTICAL COMPANY LIMITED 发明人 TOMITA NAOKI;KAJII SHIGEO;CARY DOUGLAS ROBERT;TOMITA DAISUKE;IMAMURA SHINICHI;TSUCHIDA KEN;MATSUDA SATORU;HARA RYUJIRO
分类号 C07C233/80;A61K31/167;A61K31/36;C07C235/56;C07C237/40;C07C271/22 主分类号 C07C233/80
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