发明名称 CRYSTALLINE POLYMORPHS OF ISOXAZOLINE COMPOUND AND PRODUCTION METHOD THEREOF
摘要 A method for manufacturing a crystal and a crystal of (S)-4-[5-(3,5-dichlorophenyl)-5-(trifluoromethyl)-4,5-dihydroisoxazol-3-yl]-2-methyl-N-[2-oxo-2-(2,2,2-trifluoroethylamino)ethyl]benzamide and a method for manufacturing the crystal. It is elucidated that (S)-4-[5-(3,5-dichlorophenyl)-5-(trifluoromethyl)-4,5-dihydroisoxazol-3-yl]-2-methyl-N-[2-oxo-2-(2,2,2-trifluoroethylamino)ethyl]benzamide that has a crystalline polymorph.
申请公布号 US2015005507(A1) 申请公布日期 2015.01.01
申请号 US201414317484 申请日期 2014.06.27
申请人 Nissan Chemical Industries, Ltd. 发明人 MATOBA Kazutaka;MITA Takeshi;MATSUBARA Kotatsu;KAGAMI Takahiro;NAKAHIRA Kunimitsu;KOBAYASHI Masaki;IMANAKA Hotaka;MIYACHI Rika;OHNO Masashi
分类号 C07D261/04 主分类号 C07D261/04
代理机构 代理人
主权项 1. A crystalline polymorph of (S)-4-[5-(3,5-dichlorophenyl)-5-(trifluoromethyl)-4,5-dihydroisoxazol-3-yl]-2-methyl-N-[2-oxo-2-(2,2,2-trifluoroethylamino)ethyl]benzamide that has characteristic peaks at angles of diffraction 2θ=6.56, 7.38, 11.52, 12.92, 13.19, 15.60, 16.04, 16.36, 17.59, 18.27, 18.47, 19.45, 20.62, 21.12, 22.20, 23.19, 24.59, 25.12, 25.74, and 26.48 in powder X-ray diffraction with a Cu—Kα ray.
地址 Tokyo JP