| 发明名称 |
COMPOSITIONS AND METHODS OF ALTERING CHOLESTEROL LEVELS |
| 摘要 |
The present invention relates to compositions, methods and kits using polynucleotides, primary transcripts and mmRNA molecules. |
| 申请公布号 |
US2015005372(A1) |
申请公布日期 |
2015.01.01 |
| 申请号 |
US201414454977 |
申请日期 |
2014.08.08 |
| 申请人 |
Moderna Therapeutics, Inc. |
发明人 |
Hoge Stephen G.;de Fougerolles Antonin;Ellsworth Jeff Lynn |
| 分类号 |
C07K14/705;A61K31/713;C12N9/02;A61K45/06 |
主分类号 |
C07K14/705 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
1. A composition comprising;
(a) a synthetic polynucleotide encoding PCSK9 negative LDLR, and (b) a synthetic polynucleotide encoding CYP7A1, in an acceptable diluent or carrier. |
| 地址 |
Cambridge MA US |
