发明名称 Methods of Treating Cutaneous Flushing Using Selective Alpha-2-adrenergic Receptor Agonists
摘要 The present invention relates to a method of treating, reducing, inhibiting, preventing and/or reversing cutaneous facial flushing caused by abnormal, endogenously-induced vasomotor instability associated with, but not limited to acne rosacea, menopause-associated hot flashes, hot flashes resulting from orchiectomy or ingestion of substances capable of inducing a cutaneous facial flushing reaction (e.g.: alcohol, chocolate, spices) by topical dermatological application of an effective dose of a composition comprising at least one α2 adrenergic receptor agonist (such as a (2-imidazolin-2-ylamino) quinoxaline derivative such as brimonidine tartrate)and a suitable carrier.
申请公布号 US2015031700(A1) 申请公布日期 2015.01.29
申请号 US201414513853 申请日期 2014.10.14
申请人 Scherer Warren J. 发明人 Scherer Warren J.
分类号 A61K9/00;A61K45/06;A61K31/194;A61K31/498 主分类号 A61K9/00
代理机构 代理人
主权项
地址 Naples FL US