| 摘要 |
PROBLEM TO BE SOLVED: To provide a new pH-sensitive fluorogenic dye and a related assay method suitable for monitoring phagocytosis and cell processes.SOLUTION: There is provided a compound represented by the formula (I). (Rto Rand Reach individually represents H, Z or an electron donating group (EDG), provided that Rand Rare neither hydroxyl nor thiol and not a deprotonation form thereof; Rrepresents H, alkyl, acyl, aryl, heteroaryl or the like; Rrepresents alkyl, alkenyl, acyl, aryl, cycloalkyl, a reactive group, a carrier molecule, heterocyclyl or a substituted organic group; X represents a fluorophore; Y represents =CRRor =CRR; Z represents -OR, -SRand -NRR; Rrepresents alkyl or the like; Rrepresents alkyl or the like; and Rrepresents amino or the like.) |
