METHODS AND DEVICES FOR DETECTION AND IDENTIFICATION OF ENCODED BEADS AND BIOLOGICAL MOLECULES

摘要

PROBLEM TO BE SOLVED: To provide methods and devices used in the sequencing, separation, detection, and identification of objects and biological molecules.SOLUTION: The invention relates to a DNA sequencing system which is based on cyclic sequencing by synthesis performed on beads in three-dimensional vessels, and uses monolithic multicapillary arrays for detection. In other embodiments, the invention relates to a bead comprising two or more luminescent labels coupled to a nucleic acid sequence. In further embodiments, said luminescent labels are quantum dots.